Looking back on 2025: a year of delivery, trust, and momentum
As we look back on 2025, one word stands out across everything we delivered at Creme Global: delivery.
This year was about turning deep scientific expertise into real-world impact, for regulators, industry partners, and ultimately public health. From complex regulatory submissions to predictive dashboards and AI-enabled tools, our teams delivered consistently, at scale, and with purpose.
Science that stands up to scrutiny
Throughout 2025, Creme Global continued to support some of the world’s most demanding regulatory and industry environments. We delivered major milestones, including a major Cosmetics Europe report, FDA analytics work across food safety and contaminants, scientific updates to the gold-standard Creme RIFM model, SCCS-aligned cosmetics work, WGA, fiin, plus many more.
These weren’t just technical achievements; they reinforced trust. Trust that our science is robust, transparent, and ready for real-world decision-making.
From data to foresight: predictive analytics in action
A key shift this year was moving beyond retrospective analysis toward predictive insight.
Across food safety, environmental exposure, and cosmetics, we embedded predictive models and early-warning capabilities into dashboards used by regulators and industry alike. Projects like HPAI occurrence prediction, DDT and PFAS analytics, and fresh produce risk modelling show how data, AI, and domain expertise come together to inform action, not just reporting.
AI with purpose
2025 also marked a turning point in how we use AI.
Rather than chasing hype, we focused on practical applications: automating complex workflows, improving data quality, accelerating analysis, and reducing friction for users – all with human expertise in the loop, as required. From AI-powered PDF extraction to hands-on workshops with global partners, AI became a capability, not a concept.
A stronger, smarter platform
Behind the scenes, we made significant investments in our platform: modernising the user experience, strengthening data engineering pipelines, improving security, and scaling performance.
The result is a more coherent, reliable foundation, one that supports today’s projects and tomorrow’s growth.
Powered by people
None of this happens without people. In 2025, our teams grew, collaborated across disciplines, and consistently went the extra mile. From science and engineering to design, operations and business development, delivery was a shared effort.
Our articles
Our articles published this year on our blog help reinforce the strong themes that defined Creme Global’s 2025:
- AI isn’t just a topic, it’s part of our deliverables and customer value proposition.
- Thought leadership extended beyond science to strategy and governance.
- Real-world conversations with industry experts and at global forums highlighted emerging norms and expectations for food safety, transparency, and digitalisation.
Reinforced by our Webinar series with these excellent guests.
- Sara Mortimore (former Global VP of Food Safety at Walmart).
- Dr. Andrew Wilson (former Australian food safety regulator and a Core Team Member at Cultivate SA and RiskMinds Pty Ltd.).
- Dr. Darin Detwiler (world-renowned food safety academic advisor, advocate, and author)
- Bobby Krishna (Senior Food Safety Specialist at Dubai Municipality).
- Dr. Matthew Stasiewicz (Associate Professor of Applied Food Safety in the Department of Food Science and Human Nutrition at the University of Illinois at Urbana-Champaign).
Across these conversations, this multipart series unpacked how retailers and regulators actually judge supplier performance. Common themes included:
- Resilience and readiness, not just compliance.
- The importance of risk-based evidence and data integrity.
- The role of collaboration between private and public sectors in shaping evaluation standards.
These insights offered practical takeaways for businesses aiming to meet evolving expectations from both buyers and oversight authorities.
Conferences and speaking
In 2025, Creme Global showed up, from Dublin to Washington, Vienna to San Diego, engaging directly with regulators, industry leaders, and scientific communities shaping the future of food safety and AI. Regulatory forums, Industry summits, Scientific conferences, and Partner workshops.
- 18 cities
- 9 countries
- 3 continents
Over 160,000 km travelled in 2025, all in service of science, collaboration and trust. That’s over 4 times around the Earth!
Publications
Alongside delivery and platform innovation, 2025 was also a strong year for scientific contributions at Creme Global. Our team published three complementary papers that reflect a consistent goal: making complex science more usable, transparent, and impactful for regulators, industry, and policymakers.
“In 2025, our scientific publications focused on one goal: turning complex science into knowledge that can actually be used.”
Together, these publications span AI literacy, advanced exposure science, and regulatory alignment in Europe, reinforcing Creme Global’s role at the intersection of science, technology, and real-world decision-making.
Making AI understandable and usable
A Plain-Language Beginner’s Guide to Artificial Intelligence (AI) and Machine Learning
As AI becomes increasingly embedded in risk assessment and regulatory science, this publication addressed a critical gap: understanding. Rather than focusing on algorithms, it demystified what AI and machine learning are, what they are not, and how they can be responsibly applied in scientific and regulatory contexts.
The guide emphasised transparency, explainability, and the importance of combining AI with domain expertise, themes that closely mirror how Creme Global approaches AI in practice. By making AI accessible to non-technical audiences, the paper supports more informed adoption and better cross-disciplinary collaboration.
Strengthening exposure science with PB-TK models
Physiologically Based Toxicokinetic (PB-TK) Models in Aggregate Exposure: A Review
This review paper explored the growing role of physiologically based toxicokinetic models in understanding aggregate chemical exposure. It highlighted how PB-TK models improve the scientific robustness of exposure assessment by accounting for how chemicals are absorbed, distributed, metabolised and eliminated in the body.
By examining current applications, challenges and opportunities, the paper reinforced the importance of mechanistic, biologically grounded models in regulatory science, particularly as assessments move toward cumulative and aggregate exposure frameworks.
Supporting Europe’s regulatory roadmap
EFSA Roadmap for Action for Advancing Aggregate Exposure to Chemicals in the EU
Aligned closely with European regulatory priorities, this publication examined EFSA’s roadmap for advancing aggregate exposure assessment across the EU. It outlined the scientific, data and methodological steps needed to move from concept to implementation, including harmonisation, transparency, and computational tools.
The paper positioned aggregate exposure not as a future ambition, but as an achievable goal when supported by robust data, validated models, and fit-for-purpose digital infrastructure.
Taken together, these publications reflect a consistent theme across Creme Global’s work in 2025:
- Bridging complexity and clarity, whether explaining AI or advancing exposure science
- Aligning innovation with regulation, not running ahead of it
- Supporting evidence-based decision-making with tools that are both scientifically rigorous and practically deployable
They also mirror what we delivered throughout the year: AI grounded in science, exposure models designed for real-world use, and platforms built to support evolving regulatory needs.
Looking ahead
As we head into 2026, we’re building on strong momentum: trusted partnerships, a modern platform, and a clear focus on predictive, AI-enabled science that makes a real difference.
Thank you to our clients, partners and colleagues for being part of the journey, and for helping us create a safer, healthier future through science.
Stats & impact
Platform & scale
Platform at a glance
- 2 million data rows processed
- 11,870 scientific model runs
- 120 live dashboards
- 21 data exploration workshops delivered
- 9 major hazard categories covered
Regulatory reach
Trusted by regulators worldwide
- Agencies supported include FDA, EPA, USDA, NOAA, and CFIA
- 70+ agency and industry users trained
- FDA Year 4 contract secured
Food safety & analytics
Food safety impact in 2025
- 150,417 data points harmonised, delivered, and powering clients’ analysis and dashboards.
- Early-warning predictive models are now embedded in production tools
AI & automation
AI in action
- AI-powered PDF extraction tool delivered
- Predictive analytics embedded across FDA dashboards
- AI workshops delivered to global industry partners
- Clear roadmap for AI-enabled data pipelines and modelling
Growth & visibility
Market momentum
- Major renewals and expansions with global blue-chip customers
- Global presence across ACS, IFT, IAFP, GFSI, UN, and Food Safety Summits
- Strong pipeline of next-generation, AI-led opportunities
“Behind every number is a team committed to delivering science that makes a real-world difference.”
From the whole team at Creme Global, thank you for joining us on this journey, as we look forward to a great year ahead
