Publications

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Combining databases to estimate population exposure to cosmetics and personal care products

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Authors: Comiskey Damien & Cian O’Mahony, E.J. Daly, Cronan McNamara
Publication date: 10/09/2014

Probabilistic Aggregate Exposure Modelling for a Broad Spectrum Antimicrobial in Personal Cleansing Products

Realistic estimates of chemical aggregate exposure are needed to ensure consumer safety and satisfy the requirements of regulators. In most cases, aggregate exposure is estimated simply by adding deterministic exposures from all product types containing the chemical. However, this summation will result in an unrealistically-conservative estimate since individuals vary…
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Authors: Tozer Sarah, J F Nash, and E.J. Daly
Publication date: 01/09/2013

Critical and systematic evaluation of data for estimating human exposures to 2,4-dichlorophenoxyacetic acid (2,4-D) – quality and generalizability

The herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) has been commercially available since the 1940’s. Despite decades of data on 2,4-D in food, air, soil, and water, as well as in humans, the quality the quality of these data has not been comprehensively evaluated. Using selected elements of the Biomonitoring, Environmental Epidemiology,…
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Authors: LaKind Judy S. & Carol J. Burns, Daniel Q. Naiman, Cian O’Mahony, Giulia Vilone, Annette J. Burns & Joshua S. Naiman
Publication date: 20/11/2017

A framework to determine the effectiveness of dietary exposure mitigation to chemical contaminants

In order to ensure the food safety, risk managers may implement measures to reduce human exposure to contaminants via food consumption. The evaluation of the effect of a measure is often an overlooked step in risk analysis process. The aim of this study was to develop a systematic approach…
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Authors: van der Fels-Klerx, H.J. (Ine) & Simon G. Edwards, Marc C. Kennedy, Sue O’Hagan, Cian O’Mahony, Gabriele Scholz, Pablo Steinberg, Alessandro Chiodini
Publication date: 01/12/2014

Aggregate exposure to vitamin A from cosmetics and the diet

Realism is important in estimating consumer exposure to a substance, especially when accounting for exposure from multiple sources. Humans are exposed to vitamin A from food, dietary supplements and cosmetics products. A probabilistic aggregate exposure model was developed for estimating exposure distributions to vitamin A (as retinol equivalents) in…
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Authors: Tozer S, Kosemund K, Kelly S, O’Mahony C.
Publication date: 16/10/2015

Exposure to selected preservatives in personal care products: case study comparison of exposure models and observational biomonitoring data

Exposure models provide critical information for risk assessment of personal care product ingredients, but there have been limited opportunities to compare exposure model predictions to observational exposure data. Urinary excretion data from a biomonitoring study in eight individuals were used to estimate minimum absorbed doses for triclosan and methyl-,…
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Authors: Aylward Lesa, Giulia Vilone, Christina Cowan-Ellsberry, Jon A. Arnot, John N. Westgate, Cian O’Mahony & Sean M. Hays
Publication date: 05/12/2018

FACET: Light metal packaging methodology

Agency Light metal packaging for food stuffs primarily encompasses cans, closures and aerosols. For cans used in the European Union (EU), the majority are beverage cans with about 45 billion used per annum (pa) compared to approximately 20 billion food cans. Metal closures are subdivided into about 20 billion…
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Authors: Oldring P. K. T., C. O’Mahony et al
Publication date: 03/01/2014

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