Publications

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Integrating habits and practices data for soaps, cosmetics and air care products into an existing aggregate exposure model.

In order to accurately assess aggregate exposure to a fragrance material in consumers, data are needed on consumer habits and practices, as well as the concentration of the fragrance material in those products. The present study describes the development of Phase 2 Creme RIFM model by expanding the previously…
Authors: Comiskey, Api, Barrett, Ellis, McNamara, O’Mahony, Robison, Rose, Safford, Smith, Tozer
Publication date: 27/05/2017

Application of the expanded Creme RIFM consumer exposure model to fragrance ingredients in cosmetic, personal care and air care products

As part of a joint project between the Research Institute for Fragrance Materials (RIFM) and Creme Global, a Monte Carlo model (here named the Creme RIFM model) has been developed to estimate consumer exposure to ingredients in personal care products. Details of the model produced in Phase 1 of…
Authors: Safford B & A.M.Api, C.Barratt, D.Comiskey, G.Ellis, C.McNamara, C.O’Mahony, S.Robison, J.Rose, B.Smith, S.Tozeri
Publication date: 28/02/2017

Novel database for exposure to fragrance ingredients in cosmetics and personal care products.

Exposure of fragrance ingredients in cosmetics and personal care products to the population can be determined by way of a detailed and robust survey. The frequency and combinations of products used at specific times during the day will allow the estimation of aggregate exposure for an individual consumer, and…
Authors: Comiskey D., Api AM2, Barratt C3, Daly EJ1, Ellis G4, McNamara C1, O’Mahony C1, Robison SH5, Safford B6, Smith B7, Tozer S8.
Publication date: 19/05/2015

Use of an aggregate exposure model to estimate consumer exposure to fragrance ingredients in personal care and cosmetic products.

Background: Ensuring the toxicological safety of fragrance ingredients used in personal care and cosmetic products is essential in product development and design, as well as in the regulatory compliance of the products. This requires an accurate estimation of consumer exposure which, in turn, requires an understanding of consumer habits…
Authors: Safford B., A.M.Api, C.Barratt, D.Comiskey, G.Ellis, E.J. Daly, C.McNamara, C.O’Mahony, S.Robison, B.Smith, S.Tozeri
Publication date: 01/08/2015

Aggregate exposures to existing and novel fragrances in consumer products

Authors: Tozer S, & Cian O’Mahony, Jen Hannah, John O’Brien, Seamus Kelly, Kirstin Kosemund-Meynen, Camilla Alexander-White
Publication date: 31/05/2019
publication-Present Knowledge in Food Safety A Risk-Based Approach Through the Food Chain

Exposure assessment: real-world examples of exposure models in action from simple deterministic to probabilistic aggregate and cumulative models

This chapter outlines probabilistic methods for assessing population dietary exposure. It discusses and makes recommendations on how to move from deterministic screening-type calculations to higher-tier, more refined calculations using probabilistic methods. The question of how to deal with variability and uncertainty in the exposure scenario input variables is covered….
Authors: Cronan McNamara, Sandrine Pigat
Publication date: 13/10/2022
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