Assessing and reporting uncertainties in dietary exposure analysis – Part II: Application of the uncertainty template to a practical example of exposure assessment

A previous publication described methods for assessing and reporting uncertainty in dietary exposure assessments. This follow-up publication uses a case study to develop proposals for representing and communicating uncertainty to risk managers. The food ingredient aspartame is used as the case study in a simple deterministic model (the EFSA FAIM template)…

Authors: Tennant David & Diána Bánáti, Marc Kennedy, Jürgen König, Cian O’Mahony, Susanne Kettler

Publication date: 02/08/2017

All Publications, Exposure, Food Safety, Technology

Exposure to selected preservatives in personal care products: case study comparison of exposure models and observational biomonitoring data

Exposure models provide critical information for risk assessment of personal care product ingredients, but there have been limited opportunities to compare exposure model predictions to observational exposure data. Urinary excretion data from a biomonitoring study in eight individuals were used to estimate minimum absorbed doses for triclosan and methyl-,…

Authors: Aylward Lesa, Giulia Vilone, Christina Cowan-Ellsberry, Jon A. Arnot, John N. Westgate, Cian O’Mahony & Sean M. Hays

Publication date: 05/12/2018

All Publications, Chemicals, Exposure, Personal Care

FACET: Light metal packaging methodology

Agency Light metal packaging for food stuffs primarily encompasses cans, closures and aerosols. For cans used in the European Union (EU), the majority are beverage cans with about 45 billion used per annum (pa) compared to approximately 20 billion food cans. Metal closures are subdivided into about 20 billion…

Authors: Oldring P. K. T., C. O’Mahony et al

Publication date: 03/01/2014

All Publications, Chemicals, Exposure, Migration

Next generation of microbiological risk assessment: Potential of omics data for exposure assessment

In food safety and public health risk evaluations, microbiological exposure assessment plays a central role as it provides an estimation of both the likelihood and the level of the microbial hazard in a specified consumer portion of food and takes microbial behaviour into account. While until now mostly phenotypic…

Authors: W.den Besten Heidy M., Alejandro Amézquita, Sara Bover-Cid, Stéphane Dagnas, Mariem Ellouze, Sandrine Guillou, George Nychas, Cian O’Mahony, Fernando Pérez-Rodriguez, Jeanne-Marie Membré

Publication date: 20/12/2018

All Publications, Exposure, Food Safety, Microbiology, Next Generation Sequencing

Predictive modelling of the exposure to Steviol Glycosides in Irish patients aged 1-3 years with Phenylketonuria and Cow’s milk protein allergy

Children with Phenylketonuria (PKU) and severe cow’s milk protein allergy (CMPA) consume prescribed, specially formulated, foods for special medical purposes (FSMPs) as well as restricted amounts of normal foods. These patients are exposed to artificial sweeteners from the consumption of a combination of free and prescribed foods. Young patients…

Authors: O’Sullivan Aaron J., Sandrine Pigat, Cian O’Mahony, Michael J. Gibney & Aideen I. McKevitt

Publication date: 17/11/2017

All Publications, Chemicals, Exposure, Food Safety, Nutrition

Probabilistic modelling to assess exposure to three artificial sweeteners of young Irish patients aged 1–3 years with PKU and CMPA

The choice of suitable normal foods is limited for individuals with particular medical conditions, e.g., inborn errors of metabolism (phenylketonuria – PKU) or severe cow’s milk protein allergy (CMPA). Patients may have dietary restrictions and exclusive or partial replacement of specific food groups with specially formulated products to meet…

Authors: O’Sullivan Aaron J., Sandrine Pigat, Cian O’Mahony, Michael J. Gibney & Aideen I. McKevitt

Publication date: 09/09/2016

All Publications, Chemicals, Exposure, Food Safety, Technology

Design, development and validation of software for modelling dietary exposure to food chemicals and nutrients.

The Monte Carlo computational system for stochastic modelling of dietary exposure to food chemicals and nutrients is presented. This system was developed through a European Commission-funded research project. It is accessible as a Web-based application service. The system allows and supports very significant complexity in the data sets used…

Authors: McNamara C, Naddy B, Rohan D, Sexton J.

Publication date: 20/10/2003

All Publications, Chemicals, Exposure, Food Safety, Nutrition, Technology

eBASIS (Bioactive Substances in Food Information Systems) and Bioactive Intakes: Major Updates of the Bioactive Compound Composition and Beneficial Bioeffects Database and the Development of a Probabilistic Model to Assess Intakes in Europe

eBASIS (Bioactive Substances in Food Information Systems), a web-based database that contains compositional and biological effects data for bioactive compounds of plant origin, has been updated with new data on fruits and vegetables, wheat and, due to some evidence of potential beneficial effects, extended to include meat bioactives. eBASIS…

Authors: Plumb Jenny, Sandrine Pigat, Foteini Bompola, Maeve Cushen, Hannah Pinchen, Eric Nørby, Siân Astley, Jacqueline Lyons, Mairead Kiely and Paul Finglas

Publication date: 23/03/2017

All Publications, Exposure, Nutrition, Technology

Nutrient intakes and iron and vitamin D status differ depending on main milk consumed by UK children aged 12–18 months – secondary analysis from the Diet & Nutrition Survey of Infants & Young Children.

Nutrition in the second year is important as this is a period of rapid growth and development. Milk is a major food for young children and this analysis evaluated the impact of the type of milk consumed on nutrient intakes and nutritional status. Data from the Diet and Nutrition…

Authors: Sidnell Anne, Sandrine Pigat, Sigrid Gibson, Rosalyn O’Connor, Aileen Connolly, Sylwia Sterecka, Alison M. Stephen

Publication date: 29/07/2016

All Publications, Exposure, Food Safety, Nutrition

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