A data-driven approach for prioritising microbial and chemical hazards associated with dairy products using open-source databases

This study presents a data-driven approach for classifying food safety alerts related to chemical and microbial contaminants in dairy products using the Rapid Alert System for Food and Feed (RASFF) and the World Health Organization (WHO)’s Global Environmental Monitoring System (GEMS) food contaminants databases….

Authors: Gopaiah Talari, Rajat Nag, John O’Brien, Cronan McNamara, Enda Cummins

Publication date: 15/01/2024

All Publications, Exposure, Food Safety, Microbiology, Technology

From worst-case to reality – Case studies illustrating tiered refinement of consumer exposure to cosmetic ingredients

Consumer exposure to cosmetic ingredients is estimated in a tiered manner. Simple Tier1 deterministic aggregate exposure modelling generates a worst case estimate of exposure. Tier1 assumes that a consumer uses all cosmetic products concomitantly daily, at maximum frequency, and products always contain the ingredient at the maximum allowed %…

Authors: Sarah Tozer, Camilla Alexander-White, Ripal Amin, Françoise Audebert, Catherine Barratt, John O’Brien, Tim Burke, Dagmar Bury, Hermine Dika Nguea, Myrto Dimopoulou, Sarah Farahmand, Sabrina Fritz, Elisabeth Gerber, Arianna Giusti, William Goodwin, Taryn Kirsch, Victor Oreffo, Cronan McNamara

Publication date: 01/09/2023

All Publications, Chemicals, Exposure, Fragrances, Personal Care

Read-across and new approach methodologies applied in a 10-step framework for cosmetics safety assessment – A case study with parabens

Parabens are esters of para-hydroxybenzoic acid that have been used as preservatives in many types of products for decades including agrochemicals, pharmaceuticals, food and cosmetics. This illustrative case study with propylparaben (PP) demonstrates a 10-step read-across (RAX) framework in practice. It aims at establishing a proof-of-concept for the value…

Authors: Gladys Ouedraogo a, Camilla Alexander-White b, Dagmar Bury c, Harvey J. Clewell III d, Mark Cronin e, Tom Cull f, Matthew Dent f, Bertrand Desprez g, Ann Detroyer a, Corie Ellison h, Stefania Giammanco i, Eric Hack j, Nicola J. Hewitt k, Gerry Kenna l, Martina Klaric g, Reinhard Kreiling m, Cathy Lester n, Catherine Mahony n, Enrico Mombelli o, Jorge Naciff h, John O’Brien i, Andreas Schepky p, Sarah Tozer n, Bart van der Burg q, Barbara van Vugt-Lussenburg q, Sharon Stuard h, Cosmetics Europe

Publication date: 01/05/2022

All Publications, Exposure, Fragrances, Personal Care

Microbial Risk Ranking as “a web-based decision support system” tool [Conference Paper]

WHO estimates that more than 23 million people fall ill from eating contaminated food with bacteria, viruses, and parasitic protozoa in the European region every year, resulting in 4,654 deaths and more than 400,000 DALYs. Reducing these numbers has proven challenging because of the complex European food supply chain…

Authors: Gopaiah Talari, Cronan McNamara, Enda Cummins, Rajat Nag, Kostas Koutsoumanis, John O’Brien

Publication date: 07/11/2022

All Publications, Exposure, Food Safety, Microbiology, Technology

Use of CARES NG to Conduct a Cumulative Dietary Exposure Assessment for Chlorotriazine Compounds: A Case Study

Estimation of dietary exposures to pesticide residues in agricultural and livestock commodities is critical in regulating the safe use of pesticide products. The U.S. Environmental Protection Agency (EPA) has long used the Dietary Exposure Evaluation Model-Food Commodity Intake Database (DEEM-FCID or DEEM) successfully for such purposes. Increasingly complex assessments…

Authors: Jason Johnson and Mark Breen

Publication date: 09/08/2021

All Publications, Chemicals, Exposure

Analysis of usage patterns and probabilistic risk assessment of personal care products in Korea

In daily life, many people use large amounts of personal care products (PCPs) on a regular basis. For determining the risk to consumers, product usage amount, frequency of use, and co-use patterns are essential information. In this study, the PCP usage patterns of Korean consumers were analyzed, and the…

Authors: KeunOh Choi,Namkyu Lee, Yoonhee Uhm, Joo Won Kim, Eunkyung Lim, YoungJoo Lee

Publication date: 04/10/2022

All Publications, Exposure, Personal Care

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